Eric Daniel Głowacki1

1Bioelectronics Materials and Devices Lab, CEITEC Central European Institute of Technology, Brno University of Technology, Brno, Czech Republic

A great demand exists for minimally-invasive neuromodulation technologies to enable next-generation bioelectronic medicine. This field involves using artificial electrical impulses to achieve a therapeutic outcome, and is successfully deployed in a growing range of clinical applications. Examples include Parkinson’s disease, where implanted deep brain stimulators can essentially eliminate symptoms of this condition; epilepsy, where closed-loop stimulators record pathological activity and deliver therapeutic impulses; and various spinal cord and peripheral nerve conditions. The list of applications expands constantly, as patient outcomes often are superior to what can be achieved with pharmaceutical interventions. In this presentation, I will introduce examples of bioelectronic medicine and the newest technologies that are pushing the current limits. A major focus will be minimalistic neural interface technology for selective stimulation of the nervous system. Creating minimally-invasive neuromodulation implants relies on solving advanced materials science and engineering problems. Wireless power delivery will be discussed as one of the major technical challenges in such implanted devices. I will summarize our research team’s efforts in using wireless optoelectronic technology for small and conformable nerve and brain stimulation, as well as recent advanced in noninvasive stimulation using high-frequency interfering electrical fields.

Presenting author e-mail address: glowacki@vutbr.cz